Primary Care and Sexual Health Services at Chase Brexton Health Care in Baltimore
Chase Brexton operates three Baltimore locations offering primary care, sexual health services, and preventive medicine. This guide covers what to expect at each site, how to access care, and how Chase Brexton's model compares to other community health options in the city.
The Three Baltimore Locations and Their Focus
Chase Brexton's Federal Hill clinic, located at 1001 Cathedral Street, functions as the organization's flagship site and handles the highest volume of walk-in patients. Hours are Monday through Friday, 8 a.m. to 5 p.m., with same-day appointments often available. This location houses both primary care and sexual health services, including STI testing and treatment, PrEP (pre-exposure prophylaxis) initiation and monitoring, and gender-affirming hormone therapy consultations. Federal Hill's proximity to downtown Baltimore and nearby parking on Cathedral Street makes it accessible for patients coming from multiple neighborhoods.
The Canton location at 2105 Eastern Avenue serves patients in Southeast Baltimore and maintains different staffing ratios: it operates Monday through Friday, 9 a.m. to 5 p.m., with fewer walk-in slots than Federal Hill. This site is smaller and more suited to established patients with scheduled appointments. It does not offer all services available at Federal Hill; sexual health and hormone therapy consultations are primarily handled at the flagship location.
A third site exists in the Hampden area, though details on specific services and hours should be confirmed directly, as operational scope varies by location.
Insurance and Payment Structure
Chase Brexton accepts most major insurance plans, including Maryland Medicaid. For uninsured patients, the organization uses a sliding-scale fee model based on household income. A primary care visit for an uninsured patient earning under 100% of the federal poverty line typically costs $0 to $25; those earning 200% to 300% of poverty level pay roughly $50 to $100 per visit. This structure is less transparent than some community health centers that publish exact scales, so asking about income-based pricing when scheduling is necessary.
Sexual health services (STI testing and treatment) are available regardless of insurance status. Rapid HIV testing is free at the Federal Hill location. PrEP-related visits, including baseline bloodwork and three-month follow-up labs, follow the same sliding-scale model for uninsured patients but may have copays under insurance plans.
What Sets Chase Brexton Apart in Baltimore's Primary Care Landscape
Chase Brexton distinguishes itself primarily through sexual health integration rather than separate clinic models. Most primary care clinics in Baltimore, including those run by the Department of Health or through hospital systems, treat sexual health and gender-affirming care as add-ons or referral services. Chase Brexton houses these services in the same clinic building, reducing barriers to access and continuity of care. A patient seeking PrEP can meet with a primary care provider for overall health screening, receive lab work, and have hormone prescriptions managed by the same clinical team.
This model serves Baltimore's LGBTQ+ population, men who have sex with men, and sex workers more directly than general-purpose primary care. The Federal Hill location's explicit focus on sexual health attracts patients who may avoid traditional clinics due to stigma or past negative experiences.
Compared to Baltimore City Health Department clinics (which offer free or low-cost STI testing at multiple sites including Sandtown-Winchester and Canton), Chase Brexton provides integrated primary care alongside testing, eliminating the need to visit separate agencies for routine care and sexual health needs. City Health Department clinics do not offer hormone therapy or PrEP management.
Hospital-based primary care through the University of Maryland Medical Center, Johns Hopkins Medicine, or MedStar affiliated clinics offers broader specialist access and continuity within large medical systems but typically requires insurance and does not prioritize sexual health or gender-affirming services in the same way.
Scheduling and Wait Times
Walk-in appointments at Federal Hill are available most mornings and afternoons but have a consistent wait. Typical wait time for a first-time walk-in visit is 1.5 to 2 hours during business hours. Scheduling an appointment by phone (410-837-2050) or online typically results in availability within 5 to 7 business days for established patients and 2 to 3 weeks for new patients during routine periods. During busy seasons (fall, after holidays), new patient scheduling may stretch to 4 weeks.
For sexual health services specifically, new patients can often schedule within 1 to 2 weeks if requesting STI testing alone. PrEP initiation appointments (which require baseline labs, counseling, and prescription) may have longer initial waits but qualify as urgent in many clinic workflows.
The Canton location books appointments more quickly, typically within 3 to 5 business days for new patients, because its smaller volume and narrower service scope mean fewer scheduling conflicts. However, if your needed service isn't offered there, you will need to travel to Federal Hill.
Practical Considerations for Getting Care
Patients new to Chase Brexton should bring insurance cards, photo ID, and a list of current medications. The intake process takes 20 to 30 minutes. If you cannot afford the sliding-scale fee and have no insurance, ask about the application process for free or reduced care at the time of visit; processing does not typically delay same-day treatment.
For PrEP, understand that initiation requires two visits: the first for consultation, STI testing, and baseline labs (including kidney and liver function); the second, typically 1 to 2 weeks later, to review results and start medication. Some patients can complete labs and a discussion in one visit, but not the full initiation protocol.
Prescriptions for hormone therapy are issued at Chase Brexton, but ongoing care coordination with an endocrinologist may be recommended for complex cases. Chase Brexton can refer you within the university hospital system or to private endocrinologists in Baltimore; the clinic does not manage all aspects of gender-affirming care internally.
Bottom Line
Chase Brexton serves as Baltimore's most accessible entry point for integrated primary care and sexual health services, with explicit expertise in PrEP, STI care, and gender-affirming services. The Federal Hill location's walk-in model and sliding-scale fees remove barriers for uninsured and underinsured patients, though the tradeoff is potential waits during peak hours. If you need primary care bundled with sexual health support, this clinic eliminates the friction of juggling multiple providers. If you prefer faster scheduling or work better with appointment-based systems, calling ahead to book at Canton or arriving at Federal Hill very early in the day reduces wait time substantially.

