Matthew Mardiney, MD in Baltimore: Board-Certified Allergy Care with Asthma Specialization
Advanced Asthma & Allergy Centers, led by Dr. Matthew Mardiney, is a single-provider allergy and asthma practice located in Baltimore that handles both routine allergic conditions and complex asthma management. The practice accepts most major insurance plans and operates on an appointment basis, serving patients who have been referred by a primary care physician or who self-refer for allergy testing and immunotherapy.
What Advanced Asthma & Allergy Centers actually does
Dr. Mardiney holds board certification in allergy and immunology, the credential that distinguishes specialists in this field from general practitioners who manage basic allergies. The practice focuses on two overlapping patient populations: adults with seasonal or environmental allergies, food allergies, and chronic urticaria, and patients with moderate-to-severe asthma that requires specialist oversight. This dual focus means the practice is not a general walk-in clinic but a scheduled specialty office where diagnosis and ongoing treatment are tailored to individual immune response patterns.
Services and typical appointment flow
The first visit typically includes a detailed allergy history (occupational, seasonal, food-related, and pet exposures), followed by skin prick testing if indicated. Skin testing is quick, performed on the forearm or back, and produces results within 15 minutes. The test costs vary by insurance plan; patients with commercial coverage typically pay a copay ($30 to $50, depending on their plan), while uninsured patients should confirm the out-of-pocket rate before the visit.
For patients diagnosed with environmental allergies, the practice offers subcutaneous immunotherapy (allergy shots) and sublingual immunotherapy tablets. Allergy shots require a series of build-up doses over 3 to 6 months, followed by maintenance injections every 2 to 4 weeks for up to 5 years. Each injection visit takes 30 minutes; patients must wait 15 minutes after injection to ensure no delayed reaction occurs. Immunotherapy is covered by most insurance plans, though copays apply per visit.
Asthma patients may receive pulmonary function testing (spirometry) during visits, which measures lung capacity and airflow obstruction. This test is standard for baseline asthma assessment and for monitoring response to controller medications. The practice can adjust inhalers, prescribe biologics for severe eosinophilic asthma (such as dupilumab or mepolizumab), and coordinate care with primary physicians.
How it compares to other Baltimore allergists
Baltimore has several allergists accepting most insurance plans: Dr. Stephanie Meurer at Maryland Allergy & Asthma Associates (operates multiple Maryland locations, larger multispecialty practice), and individual practitioners through hospital systems like University of Maryland Medical Center and Johns Hopkins. The key differences are scale and subspecialty depth. A multispecialty group typically offers faster new-patient appointments and may have on-site labs; a single-provider practice like Dr. Mardiney's allows longer, more focused consultations and direct continuity with one physician over time. Choose a larger group if you need urgent evaluation or if your insurance strongly prefers in-network specialists with multiple locations. Choose a single-provider practice if you prefer stable, consistent care and value the time spent on complex histories.
Who this practice suits and who it does not
Advanced Asthma & Allergy Centers is appropriate for adults with suspected allergies or asthma who have insurance (commercial, Medicare, or Medicaid) and can attend scheduled appointments. It suits patients whose symptoms do not respond to over-the-counter antihistamines or inhalers, people considering immunotherapy as a long-term treatment, and those with occupational asthma or food allergy concerns requiring formal testing.
The practice is not suitable for walk-in urgent care (such as acute anaphylaxis or severe asthma exacerbation, which belong in an emergency room), patients without referral who prefer not to schedule in advance, or families seeking pediatric-focused allergy care (the practice appears to focus on adults, though this should be confirmed directly).
First-visit logistics and hours
Appointments must be scheduled in advance; the practice does not accept walk-ins. Bring your insurance card, a photo ID, and a list of current medications. Allow 90 minutes for the first visit if testing is planned. The practice is located in Baltimore; parking availability and specific street address should be verified by calling to confirm current office location and hours of operation, as these details change.
Insurance and referral requirements
Dr. Mardiney accepts Medicare, most Blue Cross/Blue Shield plans, Cigna, Aetna, and United Healthcare; confirm your specific plan before booking. Some insurance plans require a referral from your primary care physician before the first appointment. The practice can usually accommodate new patients within 2 to 4 weeks.
This practice fills a gap between primary-care allergy management and large hospital-based specialty centers, offering depth of asthma and immunotherapy expertise without the wait times that sometimes characterize larger operations.

